Payment & Shipping Terms:
|Product Name:||2-Bromo-2',4'-dichloroacetophenone||CAS NO:||2631-72-3|
|Appearance:||White Powder||Usage:||Pharmaceutical Intermediates|
2-Bromo-2',4'-dichloroacetophenone 2,4-Dichlorophenacyl bromide CAS 2631-72-3 EINECS 220-116-7
2-bromo-2 ', 4'-dichloroacetophenone as a white powder, m.p.58 ~ 60 ℃, soluble in organic solvents, insoluble in water. Synthetic imazalil, propiconazole, a key intermediate azaconazole, B ring azoles azole fungicide. There are two methods for their preparation.
1, 2,4-dichloro-acetophenone as starting material, dissolved in chloroform, was added dropwise bromine, extends below the surface of the lower end of the dropper, was added dropwise with stirring, followed by stirring at room temperature when bromine dropwise addition 2h, was heated with stirring at reflux for 2h, the reaction was stopped, the solvent recovered by distillation of chloroform and cooled to give white crystals of ω- bromo-2,4-dichloro acetophenone.
2, p-dichlorobenzene for raw materials, first-dichlorobenzene and mixed bromo acetyl chloride in the mixture by fractional added anhydrous aluminum chloride, at below 50 ℃ for several hours, and then cooling, into ice water and layers were separated and the aqueous layer was extracted with dichloromethane and the combined organic layer, removing solvent to give ω--bromo-2,4-dichloro-acetophenone.Storage features: low temperature warehouse, ventilated and dry. Away from fire, heat source. Prevent direct sunlight. Use and storage according to specifications, the decomposition does not occur, avoid contact with the oxide.
This product is slightly hazardous for water Do not allow undiluted product or large quantities to reach ground water, water course or sewage system, without government permission, Do not allow material discharged into the surrounding environment. If used and stored according to specifications. No decomposition. Holding receptacle seal in cool, dry place to ensure that the workplace has a good ventilation or exhaust.
Safety phrases:irCauses burns.ritating substance. Irritating to eyes, respiratory system and skin. Avoid contact with skin and eyes.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing, gloves and eye/face protection.Highly flammable. Cause burns. Away from fire.I company for the production plant, complete production equipment and testing equipment.
|Other name||2,4-Dichlorophenacyl bromide|
|CAS register number||2631-72-3|
|Loss On Drying||≤0.5%||0.25%|